Immunological disorders are disease Conditions that are caused by a dysfunction of the immune system which includes allergy, asthma, autoimmune diseases, auto-inflammatory syndromes, and immunological deficiency syndromes. The place that combines neuroscience in relation with the brain system that mainly targets neuro-immunology along the interactions with the complex systems during development, response to injuries, and to a better understanding of many pathological neurological disorders which in turn contributes to a greater extent to the vaccinations and pharmacological treatments for several neurological conditions. The present research has proof that immune molecules modulate brain systems differently across lifespans.